Roy Hodgson's side set out on the road to Brazil 12 months ago with a 5-0 victory in Moldova, but any sort of win at home will suffice, with automatic qualification likely to go down to the final game.
Montenegro currently top Group H by two points, but have played a game more than England and Ukraine, who are a further point adrift in third spot.
Poland, in fourth place and five points off the summit, are not completely out of the equation either and they tackle the group leaders at home on Friday, while Ukraine meet San Marino.
The prospect of finishing top remains firmly in England's hands and, after facing Moldova, they travel to Ukraine on Tuesday before rounding off the group campaign with home dates against Montenegro and Poland in October.
Roy Hodgson goes into the game against Moldova knowing that a comfortable win will take them one step closer to qualification for the World Cup, but he knows his side must guard against complacency in Friday's World Cup Qualifier.
England currently sit two points behind Group H leaders Montenegro with a game in hand, and now is no better time to the Three Lions to get ahead of their opponents from the Baltic region.
The reverse fixture resulted in a comprehensive 5-0 victory for England at Wembley, with both Wayne Rooney and Danny Welbeck grabbing themselves a brace back in October.
Hodgson's side can seal qualification with victories in their remaining games, and with their away game against minnows Moldova, whose only win in the group being their 2-0 victory against whipping boys San Marino, many would expect a comfortable triumph in Chisinau. With that in mind, expect a few key players to be rested as a result.
Here, I focus on who the England boss has chosen to face Moldova as they prepare for Friday night's clash, which he announced at the pre-match press conference yesterday, reported by The Telegraph's Jeremy Wilson.
Caras said: "I was talking about the lucky parts of the draw but the bad one is that the other team, England, are far too good for us, unfortunately. In football a lot of things are possible and both teams have their chances.
"I do realise that our chances are very, very small - that is hard to accept but it is like this. We will try very hard, I will tell you that, but we will see the outcome on the pitch."
England team: Hart, Walker, Jagielka, Cahill, Cole, Wilshere, Gerrard, Lampard, Walcott, Lambert, Welbeck
