Scolari's men have only lost twice this year – including a 1-0 defeat against Switzerland last time out – as they prepare for the World Cup.
Barcelona star Neymar is fit to lead the attack for Felipao's men, while Alves' absence means Maicon may start at right-back with David Luiz and Thiago Silva to command the back four.
Even if some of their bigger names are rested with an eye to the Portugal clash, Brazil are likely to send Saturday's opponents a warning about what to expect from a top side at the World Cup.
Australia have friendlies against the Selecao and France as their next two clashes in what is an ideal build-up to the 2014 finals.
Australia coach Holger Osieck will learn plenty about where his team sits and has named close to a full-strength squad for the encounter in Brasilia.
The Socceroos defence will be tested by a star-studded Brazil side, so Osieck is likely to start his preferred back four in Luke Wilkshire, Lucas Neill, Sasa Ognenovski and Matt McKay.
Under the German, the Socceroos have shown they are capable of sitting back and getting results, highlighted by their 1-1 draw in Japan in a qualifier in June.
With Cahill injured, Josh Kennedy is likely to get a start up front, while Central Coast striker Mitchell Duke, who impressed at the East Asian Cup, may also get an opportunity.
Brazil vs. Australia, September 7 2013, 8:15 p.m. BST
Mane Garrincha stadium, Brasilia
Brazil take on Australia on Saturday afternoon at the Mane Garrincha stadium in Brasilia, as preparations continue apace for the World Cup next summer.
The fixture represents Luiz Felipe Scolari's side's first return to home soil since their sensational Confederations Cup victory in June, and they will hope to continue the momentum gathered in that tournament against Australia.
For the Socceroos, it is a first outing since a second-string side finished bottom of the round robin at the East Asian Cup this summer. However, with World Cup qualification assured, they will hope to use the opportunity to familiarise themselves with Brazilian conditions.
Both sides, then, have a point to prove, with Brazil having lost in their first friendly of the 2013-14 season to Switzerland last month. Both will hope to test new ideas, but also to solidify existing team structures against good opposition.
